Francis MÉGRAUD

Pubmed Publications List

 

 

 

Professor of Bacteriology at University of Bordeaux, Faculty of Medicine

Laboratoire de Bactériologie, Hôpital Pellegrin, 33076 Bordeaux cedex, France

Tel: +33 5 56 79 59 10

E-mail francis.megraud@chu-bordeaux.fr

 

Current Position

  • Consultant at Hospital Pellegrin, Bordeaux

  • Member of Team 2 of INSERM Unit 1053

  • Associate Scientific Director of the French National Reference Centre for Campylobacters & Helicobacters

 

Education

  • 1972 Diploma of Pharmacy, University of Bordeaux II

  • 1980 Doctor of Medicine, University of Bordeaux II

 

Post Graduate Training

  • 1977 Internship, Centre Hospitalier de Bordeaux, Certificate of Bacteriology, University of Bordeaux II

  • 1981 Training in cell biology research, Institute for Medical Research, Camden, New Jersey, USA

  • 1984 Epidemiology Intelligence Service Course, Center for Diseases Control, Atlanta, Georgia, USA

  • 1985 Training in Campylobacter research, Laboratory Centre for Diseases Control, Ottawa, Canada

  • 1985 Diploma for Study and Research in Human Biology, University René Descartes, Paris, France

  • 1986 Diploma for Authorisation to oversee research projects, University of Bordeaux II

Academic Appointments

  • 1978 - 1982 Assistant Professor of Bacteriology, University of Bordeaux II

  • 1982 - 1990 Associate Professor of Bacteriology, University of Bordeaux II

  • 1990 - present Professor of Bacteriology, University of Bordeaux II

Other Appointments

  • 1993 - 2017 Scientific Director of the French National reference Centre for Campylobacters and Helicobacters

  • 2007 - 2015 Head of the INSERM Unit 853 ‘Helicobacter infection, inflammation and cancer’                                    

  • 2006 - 2017 Head of the Bacteriology Department of the Bordeaux University hospital                                               
     

Awards

  •  Dr Honoris Causa of Wrocław University, Poland   2005

  •  Grants have been obtained from the World Health Organization, the Biomed I programme of the European Commission (Eurohepygast 1994-1998), the French Ministry of Foreign Affairs and a number of other institutions.

Professional Organisations

Member of: 

  • 1994 - present Elected member of the European Gastro Club

  • 1994 - present Corresponding Fellow of the Infectious Diseases, Society of America

Society and Committee Memberships

  • 1987 - present Founding member and current secretary of the European Helicobacter & Microbiota Study Group (EHMSG)  

  • 1990 - present Subcommittee of the International Union of Microbiological Societies (IUMS) for the taxonomy of Campylobacter and related organisms        

  • 1994 - 2010 Member of the International Agency for Research on Cancer (IARC) committee which first established the carcinogenic role of H. pylori infection               

  • 1994 - 2001 Elected member of the European Gastro Club

  • 1994-present Corresponding Fellow of the Infectious Diseases Society of America (IDSA)                                 

  • 1997 Secretary of the International Working Party which produced Guidelines for clinical trials aiming at the eradication of Helicobacter pylori                

  • 2003 - 2007 Member of the INSERM committee for Infectious diseases (CSS1) and for cancer (CT1)                

  • 2004 - 2011 Member of the Scientific Committee of the United Gastroenterology Federation (UEGF)              

  • 2004 - 2008 Member of the Scientific Committee of the University Victor Segalen Bordeaux 2                                 

  • 2006 - 2012 Member of the Scientific Committee of the French Institute for Health Surveillance (InVS)           

  • 2007 - 2018 Member of the ‘Conseil National des Universités’ (CNU) section 45-01                                                       

  • Member of the following societies:

  • American Gastroenterology Association (AGA),

  • American Society of Microbiology (ASM),

  • European Society of Clinical Microbiology and Infectious Diseases (ESCMID),

  • Société Française de Microbiologie (SFM),

  • Société Nationale Française de GastroEntérologie (SNFGE)

  • Société de Pathologie Infectieuse de Langue Française (SPILF)
     

  •  Co-organization of the Maastricht conferences (I to V).of the EHMSG on the Management of H. pylori infection

  • Participation at the following Consensus conferences:
    Joint EPSGHAN and NASGHAN guidelines for H. pylori in children 2011 & 2017
    EGILS (European Gastro-intestinal lymphoma study group) consensus report on MALT lymphoma 2011
    MAPS (Management of the Precancerous conditions and lesions of the Stomach) guidelines 2012 & 2018

Research Interests

  • H. pylori diagnosis and epidemiology, selected aspects of pathogenicity, gastric cancer and susceptibility to antimicrobial agents.

 

Books published

  •  Gastroduodenal pathology and Campylobacter pylori, Ed. Mégraud F., Lamouliatte H., Elsevier, Amsterdam, 1989, 659 pages.

  • Helicobacter pylori. Method for clinical diagnosis and basic research. Ed. Lee A., Mégraud F., Saunders, London, 1995, 305 pages.

  • Helicobacter pylori. Ed. Mégraud F., Lamouliatte H., Elsevier, Paris, Vol 1, 380 pages (1996). Vol 2, 500 pages (1997) in French.

    Co-editor of:

  • The Year in Helicobacter pylori (special issue of Current Opinion in Gastroenterology), Ed. Malfertheiner P., Mégraud F., Michetti P., Price A. yearly from 1994 to 2001.

  • The Year in Helicobacter (special issue of the journal Helicobacter) Ed. Mégraud F., Malfertheiner P. yearly from 2002 to 2018.

    Author of several chapters in different books published on Helicobacter pylori.

 

Publications

  • PubMed: 462 publications

  • Web of science: H index 70; 22,434 citations

  •  10 best publications on Helicobacter :
    - Mégraud F, Bonnet F, Garnier M, Lamouliatte H. Characterization of "Campylobacter pyloridis" by culture, enzymatic profile, and protein content. J Clin Microbiol. 1985;22(6):1007-10.
    - Mégraud F, Brassens-Rabbé MP, Denis F, Belbouri A, Hoa DQ. Seroepidemiology of Campylobacter pylori infection in various populations. J Clin Microbiol. 1989;27(8):1870-3.
    - Monteiro L, Bonnemaison D, Vekris A, Petry KG, Bonnet J, Vidal R, Cabrita J, Mégraud F. Complex polysaccharides as PCR inhibitors in feces: Helicobacter pylori model. J Clin Microbiol. 1997;35(4):995-8
    - Occhialini A, Urdaci M, Doucet-Populaire F, Bébéar CM, Lamouliatte H, Mégraud F. Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes.  Antimicrob Agents Chemother. 1997;41(12):2724-8
    - Marais A, Mendz GL, Hazell SL, Mégraud F. Metabolism and genetics of Helicobacter pylori: the genome era. Microbiol Mol Biol Rev. 1999;63(3):642-74.
    - Avenaud P1, Marais A, Monteiro L, Le Bail B, Bioulac Sage P, Balabaud C, Mégraud F. Detection of Helicobacter species in the liver of patients with and without primary liver carcinoma. Cancer. 2000;89(7):1431-9.
    - Broutet N, Tchamgoué S, Pereira E, Lamouliatte H, Salamon R, Mégraud F. Risk factors for failure of Helicobacter pylori therapy--results of an individual data analysis of 2751 patients. Aliment Pharmacol Ther. 2003;17(1):99-109.
    - Oleastro M1, Ménard A, Santos A, Lamouliatte H, Monteiro L, Barthélémy P, Mégraud F. Real-time PCR assay for rapid and accurate detection of point mutations conferring resistance to clarithromycin in Helicobacter pylori. J Clin Microbiol. 2003 ;41(1):397-402.
    - Malfertheiner P, Bazzoli F, Delchier JC, Celiñski K, Giguère M, Rivière M, Mégraud F; Pylera Study Group. Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial. Lancet. 2011;377:905-13.
    - Mégraud F, Coenen S, Versporten A, Kist M, Lopez-Brea M, Hirschl AM, Andersen LP, Goossens H, Glupczynski Y; Study Group participants. Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption. Gut. 2013;62(1):34-42

Editorial Boards

  • Assistant Editor of Helicobacter

  • Member of the editorial board of the following journals:
    - European Journal of Gastroenterology and Hepatology
    - Clinical Microbiology and infection
    - Minerva Gastroenterologica e Diabetologica
    - Gut and liver
    - Lancet Infectious Diseases (2001-2003)

EHMSG Core Agency

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Contact

Tel.: +43 1 405 13 83 18

Fax: +43 1 405 13 83 918

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EHMSG c/o WMA GmbH

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The EHMSG is a member of the United European Gastroenterology, a professional non-profit organisation combining all the leading European societies concerned with digestive disease.
UEG represents over 22,000 specialists, working across medicine, surgery, paediatrics, GI oncology and endoscopy. This makes UEG the most comprehensive organisation of its kind in the world, and a unique platform for collaboration and the exchange of knowledge.