For Patients-Frequently Asked Questions  
  What is it?
Helicobacter pylori is a bacterium.
It is slightly curved in the form of a helix so it was named Helicobacter. Some of its cousins are longer and you can see the helix better. Click here to see a relative
H. pylori looks like this

Click here to see a relative

The bacteria are the long squiggly ones, not the little roundish dots.
  When do you get it ?
Most people catch it before they are five or six years old. The problem is that the human stomach and its immune system can’t get rid of it by itself. As a result, helicobacter can colonize the human stomach for decades if not for life.
  Where does it come from ?

About the only place it has ever been found is the stomach of humans and some monkeys. It has been with humans for a very long time, and has been found in mummies in the Andes for instance. A whole set of cousin helicobacters colonize the stomachs of other mammals.

  What does it cause ?

Most people only get gastritis, that means an irritated stomach lining, with no pain or other symptoms. A few people who have the infection get stomach or duodenal ulcers. (The duodenum is the part just after the stomach, just before the regular small intestine begins.) A very small minority (less than one percent) of infected people get stomach cancer. Helicobacter pylori was the first bacterium to be officially recognized as a cancer-causing agent.

  What does it not cause ?

It doesn’t cause gastro-esophageal reflux disease, esophagitis, Crohn’s disease, celiac disease, inflammatory bowel disease, colon cancer or much of anything else in the intestine.

  Will I give it to my relatives ?

Probably not to other adults. We are not quite sure how it is transmitted but no one has ever been able to show transmission between spouses. Transmission probably occurs within families, most likely from child to child or from mother to child.

  How is it treated ?

Generally, the doctor will prescribe two antibiotics and an additional medicine that neutralizes stomach acid. For details on treatment, click here.

  Why so many different drugs ?

It produces a substance that neutralizes the stomach acid just around itself. Pretty slick trick, huh? Since the bacteria are well protected in the mucous lining of the stomach, they are hard to get rid of. It takes two different antibiotics and since a lot of antibiotics don’t work as well in acid, you have to take another medicine to neutralize the stomach acid. That way the antibiotics can work from the outside (inside the stomach that is) and from the inside, coming back into the stomach lining from the blood stream.

  Will I get it again ?

Probably not, re-infection rates are very, very low. Some people think that they have gotten it again when really they never got completely rid of it in the first place. Since it is hard to get rid of, sometimes the first course of antibiotics doesn’t work.

 
  Here are some useful links for more information
http://www.mayo.edu/mcj/gastro/hp.html
Helicobacter pylori and Ulcer Disease Answers to Common Questions

http://www.glaxowellcome.ch/gw/fr/public/background_hp.html
Background Info: Peptic ulcer disease H. pylori infection is found in 95 per cent of peptic ulcer patients and almost all patients with duodenal ulcer have H. pylori-related gastritis

http://cardiology.medscape.com/govmt/NIH/1999/guidelines/NIH-helico/toc-NIH-helico.html
Helicobacter pylori in Peptic Ulcer Disease. National Institutes of Health Consensus Development Conference Statement

http://www.gutdoc.com/noframes/helicobacter.html
HELICOBACTER PYLORI INFORMATION BROCHURE Helicobacter pylori is a bacterium (germ) which lives in the inner lining of the stomach. H. pylori produces a number of products which damage the lining of the stomach.

http://www.helico.com
Helicobacter pylori is a spiral shaped bacterium that lives in the stomach and duodenum (section of intestine just below stomach). It has a unique way of adapting in the harsh environment of the stomach.

 

 
   
 
European Helicobacter Study Group
European Helicobacter Study Group
 
 
 
 
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